Yuan, Chunchen published the artcileRuthenium(II)-Catalyzed C-H Difluoromethylation of Ketoximes: Tuning the Regioselectivity from the meta to the para Position, Synthetic Route of 401-55-8, the publication is Angewandte Chemie, International Edition (2018), 57(5), 1277-1281, database is CAplus and MEDLINE.
A highly para-selective CAr-H difluoromethylation of ketoxime ethers under ruthenium catalysis was developed. A wide variety of ketoxime ethers are compatible with the reaction, which leads to the corresponding para-difluoromethylated products in moderate to good yield. A mechanistic study clearly showed that chelation-assisted cycloruthenation is the key factor in the para selectivity of the difluoromethylation of ketoxime ethers. D. functional theory was used to gain a theor. understanding of the para selectivity.#.
Angewandte Chemie, International Edition published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C11H8F2, Synthetic Route of 401-55-8.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary