Woolfe, G.’s team published research in British Journal of Pharmacology and Chemotherapy in 11 | CAS: 518-67-2

British Journal of Pharmacology and Chemotherapy published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C28H29NO4, Safety of Dimidium bromide.

Woolfe, G. published the artcileTrypanocidal action of phenanthridine compounds: effect of changing the quaternary groups of known trypanocides, Safety of Dimidium bromide, the publication is British Journal of Pharmacology and Chemotherapy (1956), 330-3, database is CAplus and MEDLINE.

cf. Ann. Trop. Med. Parasitol. 46, 285(1952). The effect on trypanocidal activity of replacing the Me quaternating group of 6-(4-aminophenyl)-8-aminophenanthridinium halide and 3,8-diamino-6-alkyl (or aryl)-phenanthridinium halide with Et, Pr, or allyl was examined Trypanocidal activity measured against Trypanosoma congolense, T. brucei, T. rhodesiense, and T. gambiense was generally enhanced and was greatest with compounds originally of high activity. Toxicities for mice were also reported.

British Journal of Pharmacology and Chemotherapy published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C28H29NO4, Safety of Dimidium bromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary