Ryley, J. F.’s team published research in Annals of Tropical Medicine & Parasitology in 51 | CAS: 518-67-2

Annals of Tropical Medicine & Parasitology published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Computed Properties of 518-67-2.

Ryley, J. F. published the artcileThe chemotherapy of Babesia infections, Computed Properties of 518-67-2, the publication is Annals of Tropical Medicine & Parasitology (1957), 38-49, database is CAplus and MEDLINE.

A screening test is described for anti-Babesia drugs by using mice infected with B. rodhaini. The maximum tolerated dose and min. effective dose (as mg./20 g. × 3) are, resp.: acapron, 0.1 and 0.01; dimidium bromide, 0.5 and 0.01; ethidium bromide, 1 and 0.025; pentamidine (as base), 0.75 and 0.25; propamidine (as base), 0.5 and >0.5; stilbamidine (as base), 0.75 and 0.1; trypan blue, >5 and >5; acriflavine, 0.5 and 0.1; berenil, 0.25 and 0.1; antrycide dimethyl sulfate, 0.5 and 0.1; 4-amino-6-(2-amino-1,6-dimethyl-4-pyrimidinylamino)-2-phenyl-1-methylquinolinium dichloride (Compound 10,073), 0.5 and 0.005; bis(1,2-dimethyl-4-methylamino-6-quinolyl)-amine bis(methyl sulfate) (Compound 14,911), 1 and 0.005. Mepacrine, chloroquine, paludrine, and Daraprim had no effect against B. rodhaini. Compound 10,073, in doses up to 8 mg./kg., was effective in treating B. bovis in calves with no apparent toxicity. Reversible toxic symptoms were elicited with 10 mg./kg.

Annals of Tropical Medicine & Parasitology published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Computed Properties of 518-67-2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary