Rao, Suma published the artcileHigh resolution protein separations using affinity ultrafiltration with small charged ligands, Safety of Sodium 3-bromopropane-1-sulfonate, the publication is Journal of Membrane Science (2006), 280(1+2), 781-789, database is CAplus.
Although the feasibility of affinity ultrafiltration was demonstrated more than 20 years ago, com. applications have not developed due to the high cost and practical limitations of the large macroligands needed for highly selective separations The objective of this study was to examine the use of small charged affinity ligands for protein purification by exploiting electrostatic interactions between the charged complex and an elec.-charged membrane. Experiments were performed using bovine serum albumin and ovalbumin with Cibacron Blue as the affinity ligand. Neg. charged versions of a composite regenerated cellulose membrane were generated by covalent attachment of a sulfonic acid functionality. Binding experiments were used to identify appropriate conditions for protein separations The selectivity for the separation of BSA and ovalbumin was a function of the solution conditions, Cibacron Blue concentration, and membrane charge, with the addition of Cibacron Blue causing a 30-fold increase in selectivity. A diafiltration process was performed at the optimal conditions, giving a BSA product with a purification factor of more than 90-fold and a yield greater than 90%. These results clearly demonstrate the potential of using a small charged affinity ligand for high resolution protein separations
Journal of Membrane Science published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Safety of Sodium 3-bromopropane-1-sulfonate.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary