Li, Zhitao published the artcileAnalysis of coal tar pitch and smoke extract components and their cytotoxicity on human bronchial epithelial cells, Formula: C4Br2N2O4S, the publication is Journal of Hazardous Materials (2011), 186(2-3), 1277-1282, database is CAplus and MEDLINE.
Coal tar pitch and its smoke are considered hazardous byproducts and common pollutants generated by the coal processing industry. This work characterized coal tar pitch and its smoke extracts by gas chromatog./mass spectrometry (GC/MS) using dimethylsulfoxide. Only 0.3025% of components in total coal tar pitch were identified by GC/MS. Among 18 identified compounds, polycyclic aromatic hydrocarbons (PAH) has the highest relative abundance (0.19%). Remaining components were composed of monocyclic aromatic hydrocarbons, heterocyclic compounds, and alkenes. Among 38 coal tar pitch smoke extract constituents profiled, 87.91% were PAH; the remaining 12.09% were composed of monocyclic aromatic hydrocarbons, heterocyclic compounds, and alkenes. The cytotoxic effect of coal tar pitch and its smoke extracts on BEAS-2B cells were also evaluated using the MTT assay. BEAS-2B cells exposed to coal tar pitch exhibited a non dose-dependent, U-shaped cytotoxicity with the maximum ID of 3.75 mg/L. BEAS-2B cells exposed to coal tar pitch smoke extracts exhibited dose-dependent cytotoxicity with a 8.64 mg/L LC50. Results demonstrated the significant different composition and cytotoxicity of coal tar pitch and its extracts, suggesting 2 underlying mechanisms which are pending future investigation.
Journal of Hazardous Materials published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Formula: C4Br2N2O4S.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary