Hawkins, Shirley E. published the artcileNuclear transplantation studies of the action of dimidium bromide on ameba, Product Details of C20H18BrN3, the publication is Nature (London, United Kingdom) (1969), 222(5188), 86-7, database is CAplus and MEDLINE.
During treatment of amebas with 2.5 μg. dimidium bromide (2,7-diamino-9-phenyl-10-methylphenanthridinium bromide) (I)/mL. for 10 days, Amoeba proteus and A. discoides divided 2 and 3 times, resp., after which division ceased until death ∼20 days later. The cytoplasm of either ameba which had been exposed to I was unable to recover on receiving a homologous untreated nucleus. In contrast, an apparently I-inhibited nucleus was able to initiate division upon transplantation into homologous, untreated cytoplasm. Thus, ∼60% of the nuclei from I-treated A. discoides and 75% of those from I-treated A. proteus were able to form clones. Such clone cells derived from A. proteus responded normally (2 divisions) upon subsequent exposure to 2.5 μg. I/mL. Therefore, the target of the lethal effect of dimidium bromide in amebas seemed to be cytoplasmic rather than nuclear.
Nature (London, United Kingdom) published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Product Details of C20H18BrN3.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary