Hawkins, Shirley E. published the artcileCytoplasmic DNA-containing bodies and the response of amebas to dimidium bromide, Application of Dimidium bromide, the publication is Journal of Cell Science (1969), 5(1), 57-63, database is CAplus and MEDLINE.
The growth of Amoeba proteus (TlP) and A. discoides (TlD) in the try panocide dimidium bromide was examined At concentrations of drug between 2 and 4 μg/ml, A. proteus divided twice before inhibition and death. A. discoides was able to undergo an addnl. cycle of division before death. At other concentrations there were no differences in their response. Examination of a clone derived from the microinjection of small quantities of a. discoides cytoplasm into A. proteus revealed that the ability to divide addnl. in dimidium bromide could be transferred. Some other strains of A. proteus (DP, T4P) also resembled A. discoides in their response. All strains able to undergo an addnl. division cycle also possessed cytoplasmic DNA-containing bodies as determined by fluorescence microscopy. The difference in response to dimidium bromide observed in the 2 organisms may be associated with the presence of DNA-containing bodies in the cytoplasm of A. discoides (TlD).
Journal of Cell Science published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Application of Dimidium bromide.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary