Feng, Jian published the artcileCopper-Catalyzed 1,2,5-Trifunctionalization of Terminal Alkynes Using SR as a Transient Directing Group for Radical Translocation, Synthetic Route of 81216-14-0, the publication is Chinese Journal of Chemistry (2022), 40(14), 1667-1673, database is CAplus.
The first Cu-catalyzed 1,2,5-trifunctionalization of abundant terminal alkynes is realized by merging hydrogen atom transfer and traceless directing strategy with SR as a transient group, delivering highly functionalized aldehydes in moderate to excellent yields with broad substrate scope. The synthetic utility of this method was demonstrated by the gram-scale reaction and downstream transformations of the resultant products. Given the high efficient installation of three different functional groups in a single reaction, it can serve as a very attractive method for rapidly assembling complex mols. from readily available starting materials.
Chinese Journal of Chemistry published new progress about 81216-14-0. 81216-14-0 belongs to bromides-buliding-blocks, auxiliary class Linker,PROTAC Linker, name is 7-Bromohept-1-yne, and the molecular formula is C7H11Br, Synthetic Route of 81216-14-0.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary