Fan, Xiaozhong published the artcileEnantioselective Atropisomeric Anilides Synthesis via Cu-Catalyzed Intramolecular Adjacent C-N Coupling, Safety of 2-Bromo-5-methoxybenzene boronic acid, the publication is ACS Catalysis (2019), 9(3), 2286-2291, database is CAplus.
Catalytically asym. synthesis of atropisomeric compounds is an important research area in organic synthesis. However, in comparison with C-C atropisomers, the atropisomers caused by the restricted rotation of C-N single bonds have been given less attention because of the limited methods for accessing these compounds Herein we report a Cu-catalyzed enantioselective intramol. Ullmann-type amination reaction for the synthesis of C-N atropisomers. The C-N axial chirality was induced highly efficiently by the intramol. adjacent C-N cross-coupling. The readily prepared N,N’-(cyclohexane-1,2-diyl)dipicolinamides showed high efficacy and stereoinduction (up to 99% ee).
ACS Catalysis published new progress about 89694-44-0. 89694-44-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 2-Bromo-5-methoxybenzene boronic acid, and the molecular formula is C7H8BBrO3, Safety of 2-Bromo-5-methoxybenzene boronic acid.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary