Bian, Jianwei published the artcileEnantioselective Total Synthesis of (+)- and (-)-Nigellamine A2, Product Details of C7H13BrSi, the publication is Journal of the American Chemical Society (2006), 128(23), 7428-7429, database is CAplus and MEDLINE.
The nigellamine alkaloids are dolabellane diterpenes displaying potent lipid metabolism-promoting activity. Total synthesis of (+)- and (-)-nigellamine A2 has been accomplished. Absolute stereochem. of synthetic nigellamine A2 was established through an intramol. asym. allylic alkylation using a Pd(phosphinooxazoline) catalyst. Other notable transformations include a radical alkynylation, a diastereoselective Nozaki-Hiyama-Kishi cyclization, and a regio- and stereoselective catalytic epoxidation On the basis of X-ray crystallog. anal. of an optically active intermediate, we have confirmed the assigned absolute stereochem. of the natural product. Minor modifications of the synthetic sequence outlined here should provide access to the other nigellamine alkaloids.
Journal of the American Chemical Society published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Product Details of C7H13BrSi.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary