Negishi, Eiichi’s team published research in Tetrahedron Letters in 24 | CAS: 69361-41-7

Tetrahedron Letters published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Name: (4-Bromobut-1-yn-1-yl)trimethylsilane.

Negishi, Eiichi published the artcileSelective carbon-carbon bond formation via transition metal catalysis. 35. A convenient synthesis of unsymmetrical bibenzyls, homoallylarenes, and homopropargylarenes via palladium-catalyzed cross coupling, Name: (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Tetrahedron Letters (1983), 24(36), 3823-4, database is CAplus.

The Pd-catalyzed homobenzyl-aryl, homobenzyl-alkenyl, homoallyl-aryl, and homopropargyl-aryl cross coupling reactions provide the desired coupling products, 2-MeC6H4CH2CH2Ph, (E)-PhCH2CH2CH:CMe(CH2)5Me, 4-NCC6H4CH2CH2CH:CH2, Me3SiCCCH2CH2Ph, in high yields. Similar reactions involving alkynyl halides lead to low product yields.

Tetrahedron Letters published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Name: (4-Bromobut-1-yn-1-yl)trimethylsilane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary