Kim, Choung Un published the artcileA new class of acyclic phosphonate nucleotide analogs: Phosphonate isosteres of acyclovir and ganciclovir monophosphates as antiviral agents, Product Details of C8H15BrO2, the publication is Journal of Medicinal Chemistry (1991), 34(7), 2286-94, database is CAplus and MEDLINE.
Novel phosphonate isosteres of acyclovir (ACV) and ganciclovir (DHPG) monophosphates I (R = H, CH2OH) were found to be potent and selective antiherpesvirus agents. In the series of phosphonate analogs of ACV monophosphate, only the guanine analog I (R = H) exhibited activity against herpesviruses, similar to the structure-activity relationship observed for base modification of ACV analogs. The phosphonate isostere of ACV monophosphate I (R = H) was more effective than ACV in the HSV-1 infected mouse model. The 3′-carba analog of 9-[3-hydroxy-2-(phosphonomethoxy)propyl]purines/ pyrimidines (adenine:HPMPA; guanine:HPMPG; cytosine:HPMPC) are devoid of antiherpesvirus activity. This result confirms that the β-oxygen atom of the phosphonomethyl ether functionality in HPMP-purines/pyrimidines plays a critical role for activity against herpesviruses. The crystal structure of [(benzoyloxy)methoxy]methyladenine II was determined
Journal of Medicinal Chemistry published new progress about 97845-58-4. 97845-58-4 belongs to bromides-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Bromide, name is 5-(2-Bromoethyl)-2,2-dimethyl-1,3-dioxane, and the molecular formula is C8H15BrO2, Product Details of C8H15BrO2.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary