Bauer, Adriano published the artcileChemoselective formal β-functionalization of substituted aliphatic amides enabled by a facile stereoselective oxidation event, Safety of 7-Bromohept-1-yne, the publication is Chemical Science (2019), 10(42), 9836-9840, database is CAplus and MEDLINE.
A facile and stereoselective dehydrogenation event enabling the functionalization of aliphatic amides, e.g., 1-(indolin-1-yl)-2-methylpropan-1-one at different positions in a one-pot fashion has been described. Derivatives of relevant pharmaceuticals were formally functionalized in the β-position in late-stage manner. A single-step synthesis of incrustoporine from a simple precursor further showcases the potential utility of this approach.
Chemical Science published new progress about 81216-14-0. 81216-14-0 belongs to bromides-buliding-blocks, auxiliary class Linker,PROTAC Linker, name is 7-Bromohept-1-yne, and the molecular formula is C7H11Br, Safety of 7-Bromohept-1-yne.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary