Mravec, D.’s team published research in Cesko-Slovenska Farmacie in 24 | CAS: 56970-78-6

Cesko-Slovenska Farmacie published new progress about 56970-78-6. 56970-78-6 belongs to bromides-buliding-blocks, auxiliary class Bromide,Carboxylic acid,Aliphatic hydrocarbon chain,Inhibitor, name is 3-Bromo-2-methylpropanoic acid, and the molecular formula is C4H7BrO2, Formula: C4H7BrO2.

Mravec, D. published the artcileSynthesis of the structural analogs of LSD, Formula: C4H7BrO2, the publication is Cesko-Slovenska Farmacie (1975), 24(3), 110-15, database is CAplus.

MeNH2 added to CH2:CMeCO2Me in MeOH to give MeNHCH2CHMeCO2Me, which was hydrolyzed to the acid; PrCO2H was converted to MeNHCH2CHEtCO2Me by successive bromination, esterification with MeOH, modified Reformatskii reaction to give HOCH2CHEtCO2Me, bromination, and amination with MeNH2. CH2:CRCO2H (R = Me, Et) were successively hydrobrominated, brominated, amidated with Et2NH, and aminated with MeNH2 to give MeNHCH2CHRCONEt2. MeNHCH2CHRCOR1 (R = Me, Et; R1 = OH, OMe, NEt2) reacted with 3-(2-bromoethyl)indole (from the esterification, LiAlH4 reduction, and bromination of indole-3-acetic acid) to give 5 LSD analogs I.

Cesko-Slovenska Farmacie published new progress about 56970-78-6. 56970-78-6 belongs to bromides-buliding-blocks, auxiliary class Bromide,Carboxylic acid,Aliphatic hydrocarbon chain,Inhibitor, name is 3-Bromo-2-methylpropanoic acid, and the molecular formula is C4H7BrO2, Formula: C4H7BrO2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary