Asukabe, Hirohiko et al. published their research in Journal of Chromatography A in 1993 | CAS: 80480-15-5

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Synthetic Route of C18H11BrO

Improvement of chemical analysis of antibiotics. XX Basic study on high-performance liquid chromatographic determination of four polyether antibiotics pre-derivatized with 1-bromoacetylpyrene was written by Asukabe, Hirohiko;Murata, Hideaki;Harada, Ken-Ichi;Suzuki, Makoto;Oka, Hisao;Ikai, Yoshitomo. And the article was included in Journal of Chromatography A in 1993.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

A high-performance liquid chromatog. method for the determination of the polyether antibiotics (PEs), salinomycin (SL), monensin (MN), lasalocid (LA) and narasin (NA), based on a precolumn reaction system using 1-bromoacetylpyrene (1-BAP) as a fluorescence reagent, was established. Six standards of 1-pyrenacyl esters (PEs-PYs) including two of 1-pyrenacyl esters of internal standards, 18,19-dihydrosalinomycin (DSL) and 18,19-dihydro-20-ketosalinomycin (DKSL), were separated within 30 min on a Develosil 5C18 (5 μm) column (250×4.6 mm I.D.) with methanol-water (97:3) as the mobile phase at a flow-rate of 1.0 mL/min and were detected at λex 360 nm, λem 420 nm. This system was also effective for the separation between unused 1-BAP and PEs-PYs and the simultaneous determination of SL, MN, LA and NA was achieved at concentrations from 0.2 to 100 μg/mL. At concentrations of less than 10 μg/mL a silica gel cartridge was effective in eliminating the excess of unused reagents. Four calibration graphs with the internal standard method were linear between 20 and 100 μg/mL, 2 and 10 μg/mL and 0.2 and 1.0 μg/mL. The method is applicable to feed and residue analyses. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary