Durka, Krzysztof published the artcileThe Influence of Boronate Groups on the Selectivity of the Br-Li Exchange in Model Dibromoaryl Boronates, Product Details of C7H8BBrO2, the publication is European Journal of Organic Chemistry (2013), 2013(15), 3023-3032, database is CAplus.
The selectivity of the Br/Li exchange reaction of 6-butyl-2-(2,5-dibromophenyl)-1,3,6,2-dioxazaborocane (2,5-Br2C6H3B(OCH2CH2)2NBu) and the analogous anionic derivatives, 2,5-Br2C6H3B(OiPr)3Li and 2,5-Br2C6H3BF3K, was studied using BuLi as the lithiating reagent. In the case of the former compound there was a slight preference for lithiation at the 5-position. For 2,5-Br2C6H3B(OiPr)3Li, the lithiation occurred exclusively at C5, but for 2,5-Br2C6H3BF3K, 2-lithiation was preferred. Calculations performed for the lithiation of ortho- and meta-brominated Ph boronates revealed that ortho-lithiated aryl boronates are thermodynamically more stable, but that the Br/Li exchange is generally dictated by kinetics, which accounts for the variation of selectivity depending on the type of boronate group. The successful generation of the 2,5-dilithiophenyl boronate species 2,5-Li2C6H3B(OCH2CH2)2NBu by a double Br/Li interconversion is reported. The Br/Li exchange in the related 6-butyl-2-[3-(2,5-dibromothienyl)]-1,3,6,2-dioxazaborocane, 2,5-Br2-3-ThB(OCH2CH2)2NBu, occurred preferentially at the 5-position, but the product was readily transformed into the more stable 2-lithiated isomer. The use of 2 equiv of BuLi resulted in the efficient formation of the dilithiated species, 2,5-Li2-3-ThB(OCH2CH2)2NBu. The obtained lithiated aryl boronates were converted into functionalized arylboronic acids by treatment with selected electrophiles.
European Journal of Organic Chemistry published new progress about 1450711-53-1. 1450711-53-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Boronic Acids,Boronic Acids,Boronic acid and ester, name is (2-Bromo-5-methylphenyl)boronic acid, and the molecular formula is C7H8BBrO2, Product Details of C7H8BBrO2.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary