Rakowitz, Dietmar’s team published research in European Journal of Pharmaceutical Sciences in 27 | CAS: 76283-09-5

European Journal of Pharmaceutical Sciences published new progress about 76283-09-5. 76283-09-5 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Benzyl bromide,Benzene, name is 4-Bromo-1-(bromomethyl)-2-fluorobenzene, and the molecular formula is C7H5Br2F, COA of Formula: C7H5Br2F.

Rakowitz, Dietmar published the artcileSynthesis of novel phenylacetic acid derivatives with halogenated benzyl subunit and evaluation as aldose reductase inhibitors, COA of Formula: C7H5Br2F, the publication is European Journal of Pharmaceutical Sciences (2006), 27(2-3), 188-193, database is CAplus and MEDLINE.

In the course of our ongoing studies several substituted benzyloxyphenylacetic acids were prepared Comparison of their aldose reductase inhibition with the biol. activity obtained for recently evaluated benzoic acid analogs revealed the critical role of a methylene spacer between the aromatic core and the acidic function. Starting from the most potent derivative (i.e. 5d, IC50 = 20.9 μM) further structural modifications were performed and their influence on the inhibitory effect was established.

European Journal of Pharmaceutical Sciences published new progress about 76283-09-5. 76283-09-5 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Benzyl bromide,Benzene, name is 4-Bromo-1-(bromomethyl)-2-fluorobenzene, and the molecular formula is C7H5Br2F, COA of Formula: C7H5Br2F.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary