Mei, Wenwen published the artcileSynthesis and protein-tyrosine phosphatase 1B inhibitory activity evaluation of indolepropyl based 1,3,4-oxadiazole derivatives, Recommanded Product: 4-Bromo-1-(bromomethyl)-2-fluorobenzene, the publication is Youji Huaxue (2016), 36(3), 533-539, database is CAplus.
A series of indolepropyl based 1,3,4-oxadiazole derivatives were synthesized by esterification, hydrazidation, cyclization and substitution using indolebutyric acid as starting material. The inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was evaluated. The results indicated that five compounds displayed obviously inhibitory effect against PTP1B in vitro, for instance, compound 5g exhibited the strongest PTP1B inhibitory activity with an IC50 value of 6.74 μg·mL-1. It was the first example of indolealkyl based oxadiazole derivatives showing PTP1B inhibitory activity.
Youji Huaxue published new progress about 76283-09-5. 76283-09-5 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Benzyl bromide,Benzene, name is 4-Bromo-1-(bromomethyl)-2-fluorobenzene, and the molecular formula is C7H5Br2F, Recommanded Product: 4-Bromo-1-(bromomethyl)-2-fluorobenzene.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary