Leitner, Christian published the artcileTotal synthesis of (±)-20S-hydroxy-1,2-dehydro-pseudoaspidospermidine via a C-H activation/transannular cyclization strategy, Quality Control of 69361-41-7, the publication is Chemical Communications (Cambridge, United Kingdom) (2017), 53(54), 7451-7453, database is CAplus and MEDLINE.
A total synthesis toward the pseudoaspidospermidine family via a C-H activation/transannular cyclization strategy has been accomplished. The applicability of this approach is showcased in the concise synthesis (ten steps) of (±)-20S-hydroxy-1,2-dehydro-pseudoaspidospermidine (I) starting from known dihydropyridone II. Via a joint synthetic sequence, we were also able to address the related iboga alkaloid (±)-isovelbanamine (III) in nine steps. Key features of this synthesis are a transannular cyclization to generate the pseudoaspidospermidine skeleton (C-H activation) and a Witkop photocyclization reaction providing a 9-membered lactam. It is also worth mentioning that the joint synthetic sequence can be carried out on a multigram scale.
Chemical Communications (Cambridge, United Kingdom) published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Quality Control of 69361-41-7.
Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary