Foster, G. E.’s team published research in Analyst in 71 | CAS: 518-67-2

Analyst published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Quality Control of 518-67-2.

Foster, G. E. published the artcileAssay of 2,7-diamino-9-phenyl-10-methylphenanthridinium bromide, Quality Control of 518-67-2, the publication is Analyst (1946), 287-8, database is CAplus.

The organic compound mentioned in the title of this paper, which is more commonly known as dimidium bromide or as phenanthridium 1553 [3,8-diamino-5-methyl-6-phenylphenanthridinium bromide (C.A. numbering)], has been tested for its trypanocidal activity in the treatment of T. congolense and T. brucei infections in mice and cattle. The Br content can be easily determined by treating about 0.25 g. of sample with a little dilute HNO3 and titrating electrometrically, with AgNO3. To determine the C20H18N3+, dissolve 1 g. in 200 ml. of warm water and to the solution add 5 g. of NaOAc and 200 ml. of 0.1 M K4Fe(CN)6 with vigorous shaking. After 5 min. filter and wash the precipitate with two 25-ml. portions of water. To the filtrate add 5 ml. of concentrated HCl + 5 g. of NaCl + 2 g. KI + 3 g. ZnSO4.7-H2O. Wait for each salt to dissolve before adding the next one. After 5 min. titrate with 0.1 N Na2S2O3. After allowing for a blank, each ml. of 0.1 N K4Fe(CN)6 = 0.1141 g. of C20H18N3Br.

Analyst published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Quality Control of 518-67-2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary