Further studies on the dialkylation chemistry of [Pt2(μ-S)2(PPh3)4] with activated alkyl halides RC(O)CH2X (X = Cl, Br) was written by Ujam, Oguejiofo T.;Henderson, William;Nicholson, Brian K.;Andy Hor, T. S.. And the article was included in Inorganica Chimica Acta in 2011.Reference of 80480-15-5 The following contents are mentioned in the article:
Further studies have been carried out into the reactivity of [Pt2(μ-S)2(PPh3)4] towards a range of activated alkylating agents of the type RC(O)CH2X (R = organic moiety, e.g. Ph, pyrenyl; X = Cl, Br). Alkylation of both sulfide centers is observed for PhC(O)CH2Br, 3-(bromoacetyl)coumarin [CouC(O)CH2Br], and 1-(bromoacetyl)pyrene [PyrC(O)CH2Br], giving dications [Pt2{μ-SCH2C(O)R}2(PPh3)4]2+, isolated as their PF6– salts. The x-ray structure of [Pt2{μ-SCH2C(O)Ph}2(PPh3)4](PF6)2 shows the presence of short Pt···O contacts. In contrast, the corresponding chloro compounds [typified by PhC(O)CH2Cl] and imino analogs [e.g. PhC(NOH)CH2Br] do not dialkylate [Pt2(μ-S)2(PPh3)4]. The ability of PhC(O)CH2Br to dialkylate [Pt2(μ-S)2(PPh3)4] allows the synthesis of new mixed-alkyl dithiolate derivatives of the type [Pt2{μ-SCH2C(O)Ph}(μ-SR)(PPh3)4]2+ (R = Et or n-Bu), through alkylation of in situ-generated monoalkylated compounds [Pt2(μ-S)(μ-SR)(PPh3)4]+ (from [Pt2(μ-S)2(PPh3)4] and excess RBr). In these heterodialkylated systems ligand replacement of PPh3 occurs by the bromide ions in the reaction mixture forming monocations [Pt2{μ-SCH2C(O)Ph}(μ-SR)(PPh3)3Br]+. This ligand substitution can be easily suppressed by addition of PPh3 to the reaction mixture The complex [Pt2{μ-SCH2C(O)Ph}(μ-SBu)(PPh3)4]2+ was crystallog. characterized. X-ray crystal structures of the bromide-containing complexes [Pt2{μ-SCH2C(O)Ph}(μ-SR)(PPh3)3Br]+ (R = Et, Bu) are also reported. In both structures the coordinated bromide is trans to the SCH2C(O)Ph ligand, which adopts an axial position, while the Et and Bu substituents adopt equatorial positions, in contrast to the structures of the dialkylated complexes [Pt2{μ-SCH2C(O)Ph}2(PPh3)4]2+ and [Pt2{μ-SCH2C(O)Ph}(μ-SBu)(PPh3)4]2+ (and many other known analogs) where both alkyl groups adopt axial positions. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Reference of 80480-15-5).
2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Reference of 80480-15-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary