Tomoi, Masao published the artcilePolymer-supported bases, 4. Macrolide synthesis from ω-bromocarboxylic acids using polymer-supported 1,8-diazabicyclo[5.4.0]undec-7-ene, Synthetic Route of 56523-59-2, the main research area is macrolide synthesis polymer diazabicycloundecene; bromo carboxylic acid lactonization.
The macrolide yield in the title synthesis is a function of the degree of ring substitution and of crosslinking, which governs the effective concentration of the fixed substrate within the polymeric reagent. The effect of the polystyrene matrix on the macrolide yield in the heterogeneous system was compared with the corresponding homogeneous reaction.
Makromolekulare Chemie published new progress about Lactonization. 56523-59-2 belongs to class bromides-buliding-blocks, name is 15-Bromopentadecanoic acid, and the molecular formula is C15H29BrO2, Synthetic Route of 56523-59-2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary