Seemaisamy, Revathi published the artcileAnti-microbial and anti-cancer activity of Aegle marmelos and gas chromatography coupled spectrometry analysis of their chemical constituents, Application In Synthesis of 55099-31-5, the main research area is Staphylococcus Bacillus Aegle breast cancer cell anticancer antimicrobial.
In this study, we investigated anti-cancer and antimicrobial activity of Aegle marmelos leaf extracts and their chem. profile characterized by gas chromatog. coupled mass spectrometry (GC-MS). A. marmelos leaves were extracted with acetone, methanol, ethanol, and chloroform. Presence of phenolic compounds was identified in these extracts by qual. anal. All the extracts were subjected for anti-bacterial activity against the different strains of bacteria (Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Bacillus ariyabattai, Bacillus megaterium, Pseudomonas putida, Klebsiella pneumonia, Serratia marcescens, and Escherichia coli). It is noteworthy that acetone extract elicited maximum growth inhibition on Serratia marcescens. Based on profound anti bacterial activity, acetone and methanol extract of A. marmelos were checked for cytotoxicity against MDA-MB-231, HEp-2 and vero cells. MDA-MB-231 cells were more sensitive to acetone extract of A. marmelos with an IC50 value of 79.62 μg/mL where as HEp-2 cells are more sensitive to methanol extract of A. marmelos with an IC50 value of 47.08 μg/mL. Vero cells withstand 24 h treatment of both extract, and it is evidenced that both acetone and methanol extract of A. marmelos exhibited chemo sensitive property towards cancer cells. GCMS anal. was performed to characterize the active principles of acetone and methanol extracts of A. marmelos. GC MS data revealed the presence of ten major components. Overall, both acetone and methanol extract of A. marmelos found to be promising anti antibacterial and anti-cancer agent however the active principle of these should be isolated and characterized before reaching a concrete scientific conclusion.
International Journal of Pharmaceutical Sciences and Research published new progress about Aegle marmelos. 55099-31-5 belongs to class bromides-buliding-blocks, name is Ethyl 10-bromodecanoate, and the molecular formula is C12H23BrO2, Application In Synthesis of 55099-31-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary