Guo, Cui published the artcilePalladium-catalyzed annulation reactions of methyl o-halobenzoates with azabicyclic alkenes: a general protocol for the construction of benzo[c]phenanthridine derivatives, Application In Synthesis of 647020-71-1, the main research area is benzophenanthridine preparation palladium catalysis annulation methyl halobenzoate azabicyclic alkene.
The annulation reaction of Me o-halobenzoates with azabicyclic alkenes proceeds efficiently to give the corresponding benzo[c]phenanthridine derivatives in good to excellent yields using a developed base-free methodol. based on our preliminary studies. Thirty-seven application examples validate the compatibility of the present strategy with different groups, particularly with the electron-deficient ones, that are difficult to access using other traditional methods. In addition, annulation reactions with non-sym. azabicyclic alkenes are achieved in high regioselectivity.
RSC Advances published new progress about Cyclization. 647020-71-1 belongs to class bromides-buliding-blocks, name is Methyl 2-bromo-3-fluorobenzoate, and the molecular formula is C8H6BrFO2, Application In Synthesis of 647020-71-1.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary