Kolluru, Srinivas published the artcileNickel-Catalyzed Annulations of ortho-Haloarylimines, Safety of Ethyl 2-bromo-4-fluorobenzoate, the main research area is nickel catalyzed annulation ortho haloarylimine anti selectivity; amines; catalysis; chemometrics; kinetics; mechanism; nickel; reaction parametrization; spectroscopy; spirocycles.
We report the discovery, development, and mechanism of a nickel-catalyzed annulation reaction between o-haloarylimines and electron-poor olefins. The reaction produces two adjacent anti stereocenters and a free secondary amine. Spirocycles are formed from cyclic imines. We characterized the key oxidative addition intermediate and identified a major path leading to competing homocoupling products. The activation energy of oxidative addition and the rate of oxidative addition complex isomerization were determined The sensitivity of the reaction to reaction conditions was established in a quant. manner and both the scope and limitations of the method are presented.
ACS Catalysis published new progress about Activation energy. 651341-68-3 belongs to class bromides-buliding-blocks, name is Ethyl 2-bromo-4-fluorobenzoate, and the molecular formula is C9H8BrFO2, Safety of Ethyl 2-bromo-4-fluorobenzoate.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary