Aoyama, Hiroshi published the artcileFused heterocyclic amido compounds as anti-hepatitis C virus agents, Safety of 2-Bromo-4-methoxybenzoic acid, the main research area is fused heterocyclic amido compound preparation antiviral hepatitis C.
We identified a fused heteroaromatic amido structure based on the phenanthridine skeleton as a superior scaffold for candidate drugs with potent anti-HCV activity. Among the compounds synthesized, a phenanthridine analog with a 1,3-dioxolyl group (24) possessed the most potent anti-HCV activity (EC50 value: 50 nM), with acceptable cytotoxicity. The structural development and structure-activity relationships of these compounds are described.
Bioorganic & Medicinal Chemistry published new progress about Antiviral agents. 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Safety of 2-Bromo-4-methoxybenzoic acid.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary