Sarma, Jagarlapudi A. R. P. published the artcileSolid state nuclear bromination with N-bromosuccinimide. Part 1. Experimental and theoretical studies on some substituted aniline, phenol and nitro aromatic compounds, Quality Control of 10172-35-7, the main research area is aniline solid state nuclear bromination bromosuccinimide exptl theor; nitro aromatic solid state ring bromination bromosuccinimide exptl theor; phenol solid state nuclear bromination bromosuccinimide exptl theor.
Solid state bromination of a number of substituted phenol, aniline and nitro aromatic compounds with N-bromosuccinimide yields exclusively the nuclear brominated products. Reactivity in the solid state depends on the reaction time, temperature and nature of the substituent on the substrate. The reaction apparently proceeds by an electrophilic aromatic substitution pathway. MO and reaction free energy calculations also support such a view. Thermal anal. and video microscopic observation reveal the nature of the solid state reaction. Crystallinity is required for the reactivity and product selectivity. Product yield decreases with loss of selectivity when the reaction is carried out in a melt or in solution Unlike the topochem. solid state reactions wherein mol. packing is more important than the intrinsic reactivity, these reactions demonstrate the importance of both these factors.
Perkin 2 published new progress about AM1 (molecular orbital method). 10172-35-7 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxy-6-nitroaniline, and the molecular formula is C7H7BrN2O3, Quality Control of 10172-35-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary