Ravindernath, Anisetti published the artcileSynthesis and biological evaluation of benzo[d]imidazolyl chromeno[2,3-d]pyrimidinones, Quality Control of 156089-67-7, the main research area is benzimidazolyl chromenopyrimidinone preparation antibacterial antifungal antioxidant activity SAR.
A series of benzo[d]imidazolyl chromeno[2,3-d]pyrimidnones I (R = H, OMe, Br, Cl, R’ = H; R = R’ =Br) were described. The key intermediate 2-cyano-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)acetamide (II) is obtained by reacting 5-amino-2-mercaptobenzimidazole with Et cyanoacetate. Compound II on reaction with substituted salicylaldehydes afforded 2-imino-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromene-3-carboxamides III (R = H, OMe, Br, Cl, R’ = H; R = R’ =Br) in good yields. Compounds III (R = H, OMe, Br, Cl, R’ = H; R = R’ =Br) on condensation with formalin furnished the title compounds viz., 3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromeno[2,3-d]pyrimidin-4(3H)-ones I (R = H, OMe, Br, Cl, R’ = H; R = R’ =Br). All the synthesized compounds were screened for their anti-microbial and anti-oxidant activities.
Medicinal Chemistry Research published new progress about Antibacterial agents. 156089-67-7 belongs to class bromides-buliding-blocks, name is 4,5-Dibromo-2-hydroxybenzaldehyde, and the molecular formula is C7H4Br2O2, Quality Control of 156089-67-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary