Xu, Liangxuan published the artcileMomentary click nitrile synthesis enabled by an aminoazanium reagent, Recommanded Product: 1-Bromo-4-fluoro-2-methylbenzene, the main research area is nitrile preparation selective Schmidt reaction aminoazanium reagent.
Momentary and selective Schmidt-type nitrile synthesis was reported. The success of this achievement was ascribed to the employment of the stable and robust aminoazanium reagent H2N-DABCO. A broad range of functionalized aldehydes were efficiently converted to nitriles within 5 min at room temperature in air. The robustness and speed of the protocol allow the CHO group to be regarded as a CN equivalent in organic synthesis. Moreover, the synthetic advantage of this developed protocol is further highlighted via the direct cyanation of a diversity of aldehyde precursors (carboxylic acids, aromatics, aryl halides, alkenes and alkynes) in a cyanide-free process. Addnl., this protocol can not only be used for rapid access to a wide range of ligands and material precursors, but it can also be used in the late-stage modification of complex bioactive mols.
Organic Chemistry Frontiers published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 452-63-1 belongs to class bromides-buliding-blocks, name is 1-Bromo-4-fluoro-2-methylbenzene, and the molecular formula is C7H6BrF, Recommanded Product: 1-Bromo-4-fluoro-2-methylbenzene.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary