Wang, Qian published the artcileCopper-Catalyzed Modular Assembly of Polyheterocycles, Name: 2-Bromo-4-methoxybenzoic acid, the main research area is indenoisoquinolinone preparation; indenedione benzamide preparation cyclization copper catalyst; carboxylic acid isocyanide aldehyde ammonia Ugi reaction.
Easy operation, readily accessible starting materials, and short synthesis of the privileged scaffold indeno[1,2-c]isoquinolinones I (R1 = H, 3-MeO, 2-Me, 2-NO2, etc.; R2 = H, Me, cyclopentyl, 4-chlorophenyl, etc.; R3 = tert-Bu, benzyl, 2-methoxy-2-oxoethyl, 2-ethylphenyl, etc.; R4 = H, 8,9-dimethoxy) were achieved by an multicomponent reaction (MCR)-based protocol via an ammonia-Ugi-four component reaction (4CR)/copper-catalyzed annulation sequence. The optimization and scope and limitations of this short and general sequence are described. The methodol. allows an efficient construction of a wide variety of indenoisoquinolinones I in just two steps.
Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Name: 2-Bromo-4-methoxybenzoic acid.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary