Dethe, Dattatraya H. published the artcileAsymmetric Ru/Cinchonine Dual Catalysis for the One-Pot Synthesis of Optically Active Phthalides from Benzoic Acids and Acrylates, Product Details of C8H7BrO3, the main research area is phthalide enantioselective preparation; benzoic acid acrylate ruthenium cinchonine tandem CH activation Michael.
Herein, asym. Ru/cinchonine dual catalysis that provided straightforward access to enantioselective synthesis of C-3 substituted phthalides, e.g., I via tandem C-H activation/Michael addition was reported. The use of readily accessible and less expensive [RuCl2 (p-cym)]2 and cinchonine catalyst for the one-pot assembly of chiral phthalides greatly overcame the present trend of using highly sophisticated catalysts. The developed method provided access to both enantiomers of a product using pseudo enantiomeric cinchona alkaloids as catalysts streamlining the synthesis of phthalide in both the optically active forms.
Journal of Organic Chemistry published new progress about Benzoic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Product Details of C8H7BrO3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary