Cabre, Albert published the artcileHighly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides, Recommanded Product: (R)-tert-Butyl (2-(4-bromophenyl)propyl)carbamate, the main research area is beta aryl methyl amine preparation enantioselective; aryl allyl phthalimide hydrogenation iridium catalyst.
The iridium-catalyzed asym. hydrogenation of 2-aryl allyl phthalimides to afford enantioenriched β-aryl-β-Me amines is presented. Recently developed Ir-MaxPHOX catalysts are used for this enantioselective transformation. The mild reaction conditions and the feasible removal of the phthalimido group makes this catalytic method easily scalable and of great interest to afford chiral amines. The importance of this new methodol. is exemplified by the formal synthesis of (R)-Lorcaserin, OTS514, and enantiomerically enriched 3-Me indolines.
Organic Letters published new progress about Amines Role: SPN (Synthetic Preparation), PREP (Preparation). 211315-53-6 belongs to class bromides-buliding-blocks, name is (R)-tert-Butyl (2-(4-bromophenyl)propyl)carbamate, and the molecular formula is C14H20BrNO2, Recommanded Product: (R)-tert-Butyl (2-(4-bromophenyl)propyl)carbamate.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary