Yan, Qiaozhi published the artcileRh-Catalyzed Asymmetric Hydrogenation of α,β- and β,β-Disubstituted Unsaturated Boronate Esters, Product Details of C8H6BrFO2, the main research area is phenethyl boronate chiral preparation styrylboronate asym hydrogenation rhodium catalyst; chiral amine alc preparation asym hydrogenation styrylboronate oxidation amination; asymmetric catalysis; asymmetric hydrogenation; chiral boronate; enantioselectivity; unsaturated boronates.
Chiral phenethyl boronates ArCHRCH2Bpin and ArCH2CHRBpin were prepared by asym. hydrogenation of α- and β-substituted β-styrylboronates. A highly enantioselective hydrogenation of α,β-unsaturated boronate esters catalyzed by Rh-(S)-DTBM-Segphos complex has been developed. Both (Z)-α,β- and β,β-disubstituted substrates can be successfully hydrogenated to afford chiral boronates with excellent enantioselectivities, up to 98% ee. Furthermore, the obtained chiral boronate esters, as important versatile synthetic intermediates are successfully transformed to the corresponding chiral alcs., amines and other important derivatives with maintained enantioselectivities.
Chemistry – A European Journal published new progress about Alcohols, chiral Role: SPN (Synthetic Preparation), PREP (Preparation). 647020-71-1 belongs to class bromides-buliding-blocks, name is Methyl 2-bromo-3-fluorobenzoate, and the molecular formula is C8H6BrFO2, Product Details of C8H6BrFO2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary