Murai, Takuya published the artcileOne-Pot Preparation of (NH)-Phenanthridinones and Amide-Functionalized [7]Helicene-like Molecules from Biaryl Dicarboxylic Acids, Recommanded Product: Methyl 2-bromo-3-fluorobenzoate, the main research area is phenanthridinone amide helicene preparation; biaryl dicarboxylic acid Curtius rearrangement cyclization.
A one-pot transformation of biaryl dicarboxylic acids to (NH)-phenanthridinone derivatives based on a Curtius rearrangement and subsequent basic hydrolysis was developed. This method is also applicable for the preparation of optically active amide-functionalized [7]helicene-like mols. Furthermore, aza[5]helicene derivatives with a phosphate moiety were isolated as a product of the Curtius rearrangement step in the case of substrates that bear chalcogen atoms. The stereostructures of these products, revealed by X-ray diffraction anal., suggested that chalcogen-bonding and pnictogen-bonding interactions might contribute to their stabilization. The configurational stability of the helicene-like mols. and their chiroptical properties were further investigated.
Journal of Organic Chemistry published new progress about Base hydrolysis. 647020-71-1 belongs to class bromides-buliding-blocks, name is Methyl 2-bromo-3-fluorobenzoate, and the molecular formula is C8H6BrFO2, Recommanded Product: Methyl 2-bromo-3-fluorobenzoate.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary