Yang, Dong; Chen, Jiaming; Huang, Yanping; Pan, Huiquan; Shi, Jingqi; Zhang, Yingyue; Wang, Fang; Li, Ziyuan published their research in ACS Catalysis in 2021. The article was titled 《Room-temperature Formal Aza-Wacker Cyclization through Synergistic Copper/TEMPO-catalyzed Radical Relay》.Recommanded Product: 2623-87-2 The article contains the following contents:
A formal aza-Wacker cyclization of alkenylated carbamates or amides through a synergistic Cu/TEMPO-catalyzed radical relay pathway using N-fluorobenzenesulfonimide (NFSI) as an external oxidant afforded oxazolidinones, pyrrolidones I [R= Cl, Br, F, R1 = Me, Et, n-Pr; R2 = H, Me, Et; R1R2 = cyclohex-1-en-1-yl; X = CH2, O] and isoindolinones II [R3 = Ph, 4-MeOC6H4, OBn, etc.] under mild conditions. In this efficient cyclization of alkenylated carbamates or amides at room temperature, the imidyl nitrogen-centered radical (NCR) generated by NFSI induced carbamate or amido NCR from the substrate via N-H homolysis to realize the radical relay process, which was supported by results of control experiments In the experiment, the researchers used 4-Bromobutanoic acid(cas: 2623-87-2Recommanded Product: 2623-87-2)
4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Recommanded Product: 2623-87-2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary