In 2022,Yang, Biao; Dong, Kui; Li, Xiang-Sheng; Wu, Li-Zhu; Liu, Qiang published an article in Organic Letters. The title of the article was 《Photoacid-Enabled Synthesis of Indanes via Formal [3 + 2] Cycloaddition of Benzyl Alcohols with Olefins》.Safety of Ethyltriphenylphosphonium bromide The author mentioned the following in the article:
An environmentally friendly and high diastereoselective method for synthesizing indanes was developed via a metastable-state photoacid system containing catalytic protonated merocyanine (MEH). Under visible-light irradiation, MEH yields a metastable spiro structure and liberated protons, which facilitated the formation of carbocations from benzyl alcs., thus delivering diverse mols. in the presence of various nucleophiles. Mainly, a variety of indanes was easily obtained from benzyl alcs. and olefins and water was the only byproduct. In addition to this study using Ethyltriphenylphosphonium bromide, there are many other studies that have used Ethyltriphenylphosphonium bromide(cas: 1530-32-1Safety of Ethyltriphenylphosphonium bromide) was used in this study.
Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.Safety of Ethyltriphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary