Yan, Si-Shun; Liu, Shi-Han; Chen, Lin; Bo, Zhi-Yu; Jing, Ke; Gao, Tian-Yu; Yu, Bo; Lan, Yu; Luo, Shu-Ping; Yu, Da-Gang published an article in 2021. The article was titled 《Visible-light photoredox-catalyzed selective carboxylation of C(sp3)-F bonds with CO2》, and you may find the article in Chem.Category: bromides-buliding-blocks The information in the text is summarized as follows:
A novel selective carboxylation of C(sp3)-F bonds with CO2 via visible-light photoredox catalysis. A variety of mono-, di-, and trifluoroalkylarenes as well as α,α-difluorocarboxylic esters and amides undergo such reactions to give important aryl acetic acids and α-fluorocarboxylic acids, including several drugs and analogs, under mild conditions. Notably, mechanistic studies and DFT calculations demonstrate the dual role of CO2 as an electron carrier and electrophile during this transformation. The fluorinated substrates would undergo single-electron reduction by electron-rich CO2 radical anions, which were generated in situ from CO2 via sequential hydride-transfer reduction and hydrogen-atom-transfer processes. The experimental process involved the reaction of Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Category: bromides-buliding-blocks)
Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary