Safety of 1,4-Bis(bromomethyl)benzeneIn 2020 ,《Synthesis and properties of a stimulus-responsive block polymer》 was published in RSC Advances. The article was written by Wang, B.; Liu, F. Q.. The article contains the following contents:
In this study, the synthesis of small mols. and use of an improved “”one-pot”” method to synthesize the reversible addition-fragmentation chain transfer polymerization (RAFT) reagents have been reported. By comparing with the RAFT reagents synthesized by the traditional “”step-by-step”” method, it was observed that the reagents synthesized by the two methods had the same structure, however, the improved “”one-pot”” preparation method results in a significantly higher yield. Subsequently, two different macromol. CTA segments (PVP-CTA-PVP and PDMAEMA-CTA-PDMAEMA) were prepared by RAFT polymerization, followed by the synthesis of the block polymer PDMAEMA-b-PVP-CTA-PVP-b-PDMAEMA. Through FITR, NMR, GPC and DLS anal. of the block polymer, it was observed that the isotacticity gradually became dominant as the d.p. increased. Further, using NMR spectroscopy to study the effect of pH on the block polymer, the ionization degree of the synthesized polymer in the tumor tissue environment was observed to range between 86.32% to 99.50%, which proved that the synthesized polymers exhibit significant prospects in the medical application. In the experimental materials used by the author, we found 1,4-Bis(bromomethyl)benzene(cas: 623-24-5Safety of 1,4-Bis(bromomethyl)benzene)
1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Safety of 1,4-Bis(bromomethyl)benzene Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary