Li, Yan; Nie, Wan; Chang, Zhe; Wang, Jia-Wang; Lu, Xi; Fu, Yao published an article in 2021. The article was titled 《Cobalt-catalysed enantioselective C(sp3)-C(sp3) coupling》, and you may find the article in Nature Catalysis.Synthetic Route of C4H7Br The information in the text is summarized as follows:
Enantioselective C(sp3)-C(sp3) coupling substantially impacts organic synthesis but remains challenging. Cobalt has played an important role in the development of homogeneous organometallic catalysis, but there are few examples of its use in asym. cross-coupling. Here, a cobalt-catalyzed enantioselective C(sp3)-C(sp3) coupling reaction, namely, alkene hydroalkylation, to access chiral fluoroalkanes was reported. This reaction represents a catalyst-controlled enantioselective coupling mode in which a tailor-made auxiliary is unnecessary; via this reaction, an aliphatic C-F stereogenic center can be introduced at the desired position in an alkyl chain. In the experiment, the researchers used many compounds, for example, (Bromomethyl)cyclopropane(cas: 7051-34-5Synthetic Route of C4H7Br)
(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Synthetic Route of C4H7Br
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary