《Pd-Catalyzed Stereospecific Cross-Coupling of Chiral α-Borylalkylcopper Species with Aryl Bromides》 was published in ACS Catalysis in 2020. These research results belong to Lee, Hyesu; Lee, Soyeon; Yun, Jaesook. COA of Formula: C7H5BrO2 The article mentions the following:
Stereospecific cross-coupling of chiral α-borylalkylcopper species with aryl bromides was achieved using a Pd catalyst. The combination of a Cu catalyst and chiral NHC ligand was efficient for the generation of enantioenriched secondary α-borylorganocopper species via addition of a Cu-Bpin (= pinacol boronic ester) species to alkenyl boramides. Subsequent stereospecific cross-coupling of such organocopper nucleophiles with aryl bromides successfully proceeded with a Pd-XPhos catalyst. Using 1,2-disubstituted borylalkenes containing a 1,8-naphthalenediaminatoboryl (Bdan) group produced the corresponding anti-diborylalkanes as a single diastereomer with good enantioselectivity up to 96.5:3.5 er, and subsequent oxidation generated the corresponding anti-1,2-dihydroxyl compounds5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4COA of Formula: C7H5BrO2) was used in this study.
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.COA of Formula: C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary