In 2017,Holz, Jens; Rumpel, Katharina; Spannenberg, Anke; Paciello, Rocco; Jiao, Haijun; Boerner, Armin published 《P-Chirogenic Xantphos Ligands and Related Ether Diphosphines: Synthesis and Application in Rhodium-Catalyzed Asymmetric Hydrogenation》.ACS Catalysis published the findings.Application of 7073-94-1 The information in the text is summarized as follows:
A series of P-chirogenic Xantphos ligands and related diaryl ether diphosphines have been synthesized by a modification of the well-established Jugé method. The approach consists of the in situ deboranation of the chiral ephedrine-based phosphinite before the P-C coupling takes place. The stereochem. integrity of the stereocenters of the diphosphines during synthesis, long-time storage, and catalytic application was evaluated. In the rhodium-catalyzed asym. hydrogenation of isophorone as a model substrate for industrially relevant pro-stereogenic enones with some of the diphosphines, almost complete conversion, high chemoselectivity, and 96% ee were achieved. After reading the article, we found that the author used 1-Bromo-2-isopropylbenzene(cas: 7073-94-1Application of 7073-94-1)
1-Bromo-2-isopropylbenzene(cas: 7073-94-1) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of 7073-94-1 Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary