《Dipolar HCP materials as alternatives to DMF solvent for azide-based synthesis》 was published in Green Chemistry in 2021. These research results belong to Gao, Feng; Bai, Rongxian; Li, Minghao; Gu, Yanlong. Electric Literature of C7H5Br2F The article mentions the following:
Hypercrosslinked polymers HCP-DMF and HCP-DMF-SO3H containing abundant and flexible DMF moieties were designed and synthesized. Benefitting from the solvation microenvironment provided by the pseudo-DMF moities, the polar HCPs manifested outstanding performances in the conversions of NaN3 to benzylic azides and 1,2,3-triazoles in EtOH (95%), resp., avoiding the use of risky DMF and improving the separation processes of the products. The experimental part of the paper was very detailed, including the reaction process of 4-Bromo-1-(bromomethyl)-2-fluorobenzene(cas: 76283-09-5Electric Literature of C7H5Br2F)
4-Bromo-1-(bromomethyl)-2-fluorobenzene(cas: 76283-09-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Electric Literature of C7H5Br2F
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary