《An effective synthesis of ursodeoxycholic acid from dehydroepiandrosterone》 was written by Chen, Wang; Hu, Daihua; Feng, Zili; Liu, Zhaopeng. HPLC of Formula: 1530-32-1This research focused onursodeoxycholic acid preparation Mitsunobu inversion Luche regioselective allyl oxidation; Dehydroepiandrosterone; Synthesis; Ursodeoxycholic acid. The article conveys some information:
A novel synthetic route of producing ursodeoxycholic acid (UDCA, I) was developed through multiple reactions from plant-source dehydroepiandrosterone (DHEA), with a Mitsunobu reaction and regioselective allyl oxidationat as the key steps. The reaction conditions of the key allyl oxidation reaction were also investigated and optimized, including solvent, oxidant and reaction temperature In this novel route for the preparation of UDCA, most of the reaction steps have high conversions and overall yield up to 35% for 8 steps. Since all starting materials are cost-effective, com. available and effectively avoided the risk of animal derived raw materials, this promising synthetic route offers economical and efficient strategies for potential production of UDCA. In the experimental materials used by the author, we found Ethyltriphenylphosphonium bromide(cas: 1530-32-1HPLC of Formula: 1530-32-1)
Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.HPLC of Formula: 1530-32-1
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary