Zuo, Hang-Dong; Zhu, Shan-Shan; Hao, Wen-Juan; Wang, Shi-Chao; Tu, Shu-Jiang; Jiang, Bo published their research in ACS Catalysis in 2021. The article was titled 《Copper-Catalyzed Asymmetric Deconstructive Alkynylation of Cyclic Oximes》.Recommanded Product: 1-Bromo-3,4,5-trimethoxybenzene The article contains the following contents:
A general asym. deconstructive alkynylation of cyclic oximes with terminal alkynes was reported using copper/chiral cinchona alkaloid-based N,N,P-ligand catalysts and used to produce more than 60 examples of enantioenriched γ- and δ-alkynyl nitriles in a highly functional group-compatible manner. A wide variety of low-cost terminal alkynes and easily available cyclic oximes with substituent diversity were found to be well tolerated with the current asym. transformation with good functional group tolerance. The resulting chiral alkynyl nitriles were intermediates, which could be converted into skeletally diverse chiral mols., including δ-alkynyl amides, ε-alkenyl carbamate, and ζ-keto nitrile, under suitable reaction conditions. After reading the article, we found that the author used 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Recommanded Product: 1-Bromo-3,4,5-trimethoxybenzene)
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Referemce:
Bromide – Wikipedia,
bromide – Wiktionary