In 2022,Yu, Wan-Lei; Ren, Zi-Gang; Ma, Wei; Zheng, Haixue; Wu, Wangsuo; Xu, Peng-Fei published an article in Green Chemistry. The title of the article was 《Intramolecular dehydrogenative amination of alkenes via dual organic photoredox and cobalt catalysis without a hydrogen acceptor》.Application In Synthesis of 4-Bromobutanoic acid The author mentioned the following in the article:
A conceptually novel oxidant-free dehydrogenative amination of alkenes I (Ar = Ph, 4-Me-ph, naphthalen-1-yl, etc.; R1 = H, Me, Ph, Et, etc.; R2 = H, Me, Et; R1R2 = cyclohexyl, 1-[(tert-butoxy)(oxo)methane]piperidin-4-yl, cyclopentyl, etc.; X = CH2, O, N, S) through a synergistic photoredox and cobalt catalysis with H2 evolution has been achieved. With this approach, a wide range of five-membered N-heterocycles II and III (R3 = Ph, 2,4,6-trimethylphenyl, 2-phenylethyl, etc.) was synthesized with excellent atom-economy. The green system will address the challenges that are sensitive to traditionally oxidative conditions. Furthermore, the scope and mechanistic details of the method are discussed. The experimental part of the paper was very detailed, including the reaction process of 4-Bromobutanoic acid(cas: 2623-87-2Application In Synthesis of 4-Bromobutanoic acid)
4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Application In Synthesis of 4-Bromobutanoic acid
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary