《Rh-Catalyzed Annulation of Benzoic Acids, Formaldehyde, and Malonates via ortho-Hydroarylation to Indanones》 was published in Organic Letters in 2020. These research results belong to Yu, Shuling; Lv, Ningning; Hong, Chao; Liu, Zhanxiang; Zhang, Yuhong. Product Details of 76006-33-2 The article mentions the following:
A three-component reaction from readily available low-cost materials of benzoic acids, formaldehyde, and malonates for the preparation of indanones by rhodium catalysis is reported. The annulation is initiated by an ortho-hydroarylation of benzoic acids, and a Lewis acid is not required. The solvent has a significant influence to the reaction, and 2-substituted or nonsubstituted indanones are obtained by the change of solvent. In addition to this study using 3-Bromo-2-methylbenzoic acid, there are many other studies that have used 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Product Details of 76006-33-2) was used in this study.
3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals.Product Details of 76006-33-2 The most pervasive is the naturally produced bromomethane.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary