《Microwave-assisted unprotected Sonogashira reaction in water for the synthesis of polysubstituted aromatic acetylene compounds》 was written by Tian, Yucheng; Wang, Jubo; Cheng, Xinying; Liu, Kang; Wu, Tizhi; Qiu, Xiaqiu; Kuang, Zijian; Li, Zhiyu; Bian, Jinlei. Product Details of 4316-58-9 And the article was included in Green Chemistry in 2020. The article conveys some information:
A microwave-assisted, efficient and rapid Sonogashira reaction was developed for the synthesis of polysubstituted aromatic alkynes. The reaction was made environmentally friendly and easy to perform by replacing the traditional amine solvents with H2O. The optimized reaction conditions yielded the products with high yields, while reducing the dependence on anaerobic reaction conditions with no inert gas protection. The reaction also achieved the product on the milligram level, overcoming the problem of TMSA volatilization in small-scale reactions. The environmentally friendly reaction solvent, mild reaction conditions, high reaction yields and short reaction time made the reaction highly promising for various applications, especially for synthesizing porous aromatic frameworks. In the experiment, the researchers used many compounds, for example, Tris(4-bromophenyl)amine(cas: 4316-58-9Product Details of 4316-58-9)
In other references, Tris(4-bromophenyl)amine(cas: 4316-58-9) is often used in the synthesis of porous luminescent covalent–organic polymers (COPs)Product Details of 4316-58-9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary