《Ligand-Enabled Pd(II)-Catalyzed C(sp3)-H Lactonization Using Molecular Oxygen as Oxidant》 was written by Qian, Shaoqun; Li, Zi-Qi; Li, Minyan; Wisniewski, Steven R.; Qiao, Jennifer X.; Richter, Jeremy M.; Ewing, William R.; Eastgate, Martin D.; Chen, Jason S.; Yu, Jin-Quan. Synthetic Route of C8H7BrO2 And the article was included in Organic Letters in 2020. The article conveys some information:
Pd(II)-catalyzed C-H lactonization of o-Me benzoic acid substrates has been achieved using mol. oxygen as the oxidant. This finding provides a rare example of C-H oxygenation through Pd(II)/Pd(0) catalysis as well as a method to construct biol. important benzolactone scaffolds. The use of a gas mixture of 5% oxygen in nitrogen demonstrated the possibility for its application in pharmaceutical manufacturing In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Synthetic Route of C8H7BrO2)
3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Synthetic Route of C8H7BrO2 Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary