Li, Cai-Yi; Ma, Yue; Lei, Zhi-Wei; Hu, Xiang-Guo published their research in Organic Letters in 2021. The article was titled 《Glycosyl-Radical-Based Synthesis of C-Alkyl Glycosides via Photo-mediated Defluorinative gem-Difluoro-allylation》.COA of Formula: C13H17BrO9 The article contains the following contents:
We have developed a stereoselective, glycosyl radical-based method for the synthesis of C-alkyl glycosides via a photo-mediated defluorinative gem-difluoroallylation reaction. We demonstrate for the first time that glycosyl radicals, generated from glycosyl bromides, can readily participate in a photo-mediated radical polar crossover process, affording a diverse array of gem-difluoro-alkene containing C-glycosides. Notable features of this method include scalability, mild conditions, broad substrate scope, and suitability for the late-stage modification of complex mols. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3COA of Formula: C13H17BrO9)
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.COA of Formula: C13H17BrO9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary