《Effect of Aryl Ligand Identity on Catalytic Performance of Trineopentylphosphine Arylpalladium Complexes in N-Arylation Reactions》 was written by Hu, Huaiyuan; Burlas, Corrie E.; Curley, Sabrina J.; Gruchala, Tomasz; Qu, Fengrui; Shaughnessy, Kevin H.. Computed Properties of C7H5BrO2 And the article was included in Organometallics in 2020. The article conveys some information:
Air-stable [(Np3P)Pd(Ar)Br]2 (Np = neopentyl) and (Np3P)Pd(Ar)(amine)Br complexes (amine = morpholine and isobutylamine) were prepared and tested as precatalysts for the coupling of sterically demanding aryl bromides and aniline derivatives The complexes are more active than the catalyst generated in situ from Pd2(dba)3 and PNp3. Increasing steric demand of the aryl group on Pd correlates with increased catalyst activity. Reactions catalyzed by [(Np3P)Pd(2,6-Me2C6H3)Br]2 occur efficiently at lower temperatures and with similar or higher yields than those using Pd2(dba)3/PNp3. The amine adducts give lower reaction rates and conversion to product than the [(Np3P)Pd(Ar)Br]2 complexes. The lower activity of the amine adducts appears to result from slow base-promoted reductive elimination to generate the catalytically active LPd(0) species. The results came from multiple reactions, including the reaction of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Computed Properties of C7H5BrO2)
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Computed Properties of C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary